Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048544 | 0.82 | KDM4E (0.53) | KDM4EMAPTSMN1; SMN2LMNATDP1 | |
| SCHEMBL19697639 | 0.77 | SMN1; SMN2 (0.51) | KDM4EMAPTSMN1; SMN2LMNAADRB2 | |
| SCHEMBL30938605 | 0.77 | SMN1; SMN2 (0.51) | KDM4EMAPTSMN1; SMN2LMNAADRB2 | |
| SCHEMBL29331705 | 0.76 | AR (0.43) | KDM4EMAPTSMN1; SMN2LMNAADRB2 | |
| SCHEMBL31420086 | 0.75 | KDM4E (0.38) | KDM4EMAPTSMN1; SMN2LMNAADRB2 | |
| SCHEMBL26986671 | 0.75 | KDM4E (0.38) | KDM4EMAPTSMN1; SMN2LMNAADRB2 | |
| SCHEMBL31127281 | 0.74 | KDM4E (0.36) | KDM4EMAPTSMN1; SMN2LMNAADRB2 | |
| SCHEMBL7052498 | 0.74 | KDM4E (0.36) | KDM4EMAPTSMN1; SMN2LMNAADRB2 | |
| SCHEMBL29331661 | 0.73 | CACNA1H (0.39) | KDM4E | |
| SCHEMBL25762549 | 0.73 | HRH3 (0.40) | KDM4EMAPTSMN1; SMN2LMNAADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |