Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20617704 | 0.79 | SOS1 (0.35) | TSHR | |
| SCHEMBL21704583 | 0.77 | TSHR (0.54) | TSHR | |
| SCHEMBL18976595 | 0.77 | TSHR (0.54) | TSHR | |
| SCHEMBL21981462 | 0.75 | — | — | |
| SCHEMBL24387896 | 0.75 | TSHR (0.34) | TSHR | |
| SCHEMBL24717318 | 0.75 | — | — | |
| SCHEMBL20669237 | 0.74 | — | — | |
| SCHEMBL24372978 | 0.74 | — | — | |
| SCHEMBL21341820 | 0.74 | — | — | |
| SCHEMBL23055723 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151557-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |