Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 18/20 | 0.64 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.54 |
| ▸ | TPH1 | P17752 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2932163 | 0.88 | S1PR1 (0.66) | S1PR1S1PR5TPH1 | |
| SCHEMBL2934453 | 0.86 | S1PR1 (0.61) | S1PR1S1PR5 | |
| SCHEMBL2933616 | 0.85 | S1PR1 (0.62) | S1PR1S1PR5 | |
| SCHEMBL2935613 | 0.84 | S1PR1 (0.44) | S1PR1S1PR5 | |
| SCHEMBL2936062 | 0.84 | S1PR1 (0.51) | S1PR1S1PR5 | |
| SCHEMBL2937505 | 0.83 | S1PR1 (0.48) | S1PR1S1PR5 | |
| SCHEMBL2930307 | 0.80 | MAP4K4 (0.59) | S1PR1S1PR5 | |
| SCHEMBL2934653 | 0.79 | S1PR1 (0.57) | S1PR1S1PR5 | |
| SCHEMBL20615475 | 0.78 | S1PR1 (1.00) | S1PR1S1PR5 | |
| SCHEMBL2936368 | 0.78 | S1PR1 (0.54) | S1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091950-B1 | OXADIAZOLE DERIVATIVES AS S1P1 RECEPTOR AGONISTS | GLAXO GROUP LTD (GB) | 2010-09-22 | — | — | EP | claimed |