SCHEMBL29338346

SCHEMBL29338346

Cn1cc(-c2cc(Sc3ccccc3C#N)c3c(C#N)cnn3c2)cn1

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RET P07949 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31131199 1.00 RET (0.52) RET
SCHEMBL31131253 0.93 RET (0.45) RET
SCHEMBL29340517 0.90 RET (0.53) RET
SCHEMBL29340939 0.89 RET (0.54) RET
SCHEMBL29340655 0.89 RET (0.55) RET
SCHEMBL29338485 0.87 RET (0.41) RET
SCHEMBL31130940 0.87 RET (0.41) RET
SCHEMBL29340631 0.86 RET (0.53) RET
SCHEMBL31131178 0.86 RET (0.53) RET
SCHEMBL29338949 0.86 RET (0.53) RET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151638-A2 COMPOUNDS FOR FGFRS INHIBITORS COGENT BIOSCIENCES, INC. (US) 2024-07-18 WO disclosed