Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29338470 | 0.82 | PDGFRB (0.52) | PDGFRBPDGFRATP53RAB9ANPC1 | |
| SCHEMBL1530816 | 0.81 | PDGFRB (0.55) | PDGFRBPDGFRATP53RAB9ANPC1 | |
| SCHEMBL29338718 | 0.80 | PDGFRB (0.49) | PDGFRBPDGFRATP53RAB9ANPC1 | |
| SCHEMBL29338750 | 0.78 | CSF1R (0.46) | PDGFRBPDGFRARAB9ANPC1GAA | |
| SCHEMBL29338736 | 0.78 | PDGFRB (0.52) | PDGFRBPDGFRATP53RAB9ACLK4 | |
| SCHEMBL558386 | 0.77 | PDGFRB (0.54) | PDGFRBPDGFRARAB9ANPC1TSHR | |
| SCHEMBL782184 | 0.75 | CLK4 (0.50) | PDGFRBPDGFRARAB9ANPC1CLK4 | |
| SCHEMBL1530858 | 0.73 | PDGFRB (0.47) | PDGFRBPDGFRATP53RAB9ANPC1 | |
| SCHEMBL31663349 | 0.73 | MEN1 (0.49) | PDGFRBPDGFRATP53RAB9ACLK4 | |
| SCHEMBL558073 | 0.72 | FGFR3 (0.56) | PDGFRBPDGFRARAB9ANPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148272-A1 | AZA BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS | RIBOSCIENCE LLC (US) | 2024-07-11 | — | — | WO | disclosed |