Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18793924 | 0.80 | MAPK1 (0.69) | MAPK1 | |
| SCHEMBL29338808 | 0.70 | MAPK1 (0.48) | MAPK1 | |
| SCHEMBL20738765 | 0.68 | MAPK1 (0.54) | MAPK1 | |
| SCHEMBL29676126 | 0.66 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL18765716 | 0.66 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL29339032 | 0.66 | MAPK1 (0.52) | MAPK1 | |
| SCHEMBL20738622 | 0.65 | MAPK1 (0.66) | MAPK1 | |
| SCHEMBL18766074 | 0.64 | MAPK1 (0.57) | MAPK1 | |
| SCHEMBL18765806 | 0.64 | MAPK1 (0.67) | MAPK1 | |
| SCHEMBL30926269 | 0.63 | BRD4 (0.38) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |