Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18765806 | 0.88 | MAPK1 (0.67) | MAPK1 | |
| SCHEMBL29338666 | 0.83 | MAPK1 (0.57) | MAPK1 | |
| SCHEMBL18765621 | 0.83 | MAPK1 (0.70) | MAPK1 | |
| SCHEMBL29339380 | 0.83 | MAPK1 (0.55) | MAPK1 | |
| SCHEMBL18765987 | 0.83 | MAPK1 (0.74) | MAPK1 | |
| SCHEMBL18765934 | 0.82 | MAPK1 (0.58) | MAPK1 | |
| SCHEMBL29339345 | 0.82 | MAPK1 (0.61) | MAPK1 | |
| SCHEMBL18793713 | 0.82 | MAPK1 (0.68) | MAPK1 | |
| SCHEMBL18765639 | 0.81 | MAPK1 (0.84) | MAPK1 | |
| SCHEMBL18765641 | 0.81 | MAPK1 (0.84) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |