Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.47 |
| ▸ | SRC | P12931 | 5/20 | 0.46 |
| ▸ | BRAF | P15056 | 5/20 | 0.46 |
| ▸ | KDR | P35968 | 5/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2931973 | 0.79 | MAPK14 (0.53) | MAPK14SRCBRAFKDRCSNK1A1 | |
| SCHEMBL2931830 | 0.71 | MAPK14 (0.48) | MAPK14CSNK1A1CSNK1DCSNK1ERAF1 | |
| SCHEMBL2926530 | 0.69 | MAPK14 (0.52) | MAPK14SRCBRAFKDRCSNK1A1 | |
| SCHEMBL2932183 | 0.68 | MAPK14 (0.53) | MAPK14SRCBRAFKDRCSNK1A1 | |
| SCHEMBL2929217 | 0.68 | MAPK14 (0.50) | MAPK14SRCBRAFKDRCSNK1A1 | |
| SCHEMBL4411198 | 0.67 | MAPK14 (0.51) | MAPK14SRCBRAFKDRCSNK1A1 | |
| SCHEMBL1384721 | 0.67 | MAPK14 (0.48) | KDM4EMAPK14SRCBRAFKDR | |
| SCHEMBL2931965 | 0.66 | MAPK14 (0.47) | MAPK14BRAFCSNK1A1CSNK1DCSNK1E | |
| SCHEMBL4417409 | 0.66 | MAPK14 (0.46) | MAPK14SRCBRAFKDRCSNK1A1 | |
| SCHEMBL2930745 | 0.66 | MAPK14 (0.51) | MAPK14CSNK1A1CSNK1DCSNK1EEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611131-B1 | PYRAZOLOPYRIDINE DERIVATES | PALAU PHARMA SA (ES) | 2010-09-15 | — | — | EP | claimed |