Cypenamine

Cypenamine

SCHEMBL293404

NC1CCCC1c1ccccc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 10/20 0.60
MAOB P27338 9/20 0.60
MAOA P21397 7/20 0.60
CYP2C19 P33261 4/20 0.60
CYP2B6 P20813 3/20 0.60
CYP1A2 P05177 2/20 0.60
CYP2D6 P10635 2/20 0.60
CYP2C9 P11712 2/20 0.60
LMNA P02545 2/20 0.60
TAAR1 Q96RJ0 2/20 0.60
CYP3A4 P08684 1/20 0.60
HTR1A P08908 1/20 0.60
ADRA2A P08913 1/20 0.60
CYP2A6 P11509 1/20 0.60
SLC6A2 P23975 1/20 0.60
HTR2C P28335 1/20 0.60
ADRA1A P35348 1/20 0.60
DRD3 P35462 1/20 0.60
SLC6A3 Q01959 1/20 0.60
KCNH2 Q12809 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cypenamine SCHEMBL13813781 1.00 KDM1A (0.60) KDM1AMAOBMAOACYP2C19CYP2B6
Cypenamine SCHEMBL293405 1.00 KDM1A (0.60) KDM1AMAOBMAOACYP2C19CYP2B6
Cypenamine SCHEMBL4418958 1.00 KDM1A (0.60) KDM1AMAOBMAOACYP2C19CYP2B6
Cypenamine SCHEMBL295252 1.00 KDM1A (0.60) KDM1AMAOBMAOACYP2C19CYP2B6
Cypenamine SCHEMBL12261999 1.00 KDM1A (0.60) KDM1AMAOBMAOACYP2C19CYP2B6
Cypenamine SCHEMBL7307497 0.98 MAOB (0.61) KDM1AMAOBMAOACYP2C19CYP2B6
Cypenamine SCHEMBL119769 0.98 MAOB (0.61) KDM1AMAOBMAOACYP2C19CYP2B6
Cypenamine SCHEMBL7316865 0.98 MAOB (0.61) KDM1AMAOBMAOACYP2C19CYP2B6
SCHEMBL10494836 0.95 MAOB (0.60) KDM1AMAOBMAOACYP2C19CYP2B6
SCHEMBL12261925 0.95 MAOB (0.60) KDM1AMAOBMAOACYP2C19CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200060997-A1 TARR Receptor Agonists for Sexual Dysfunction JOHN MCCOY 2020-02-27 US claimed
US-20160000815-A1 COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC DISORDERS GOSFORTH CT HOLDINGS PTY LTD (AU) 2016-01-07 US claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
EP-2729216-A1 PHARMACEUTICAL COMPOSITION FOR NEUROLOGICAL DISORDERS Gosforth Centre (Holdings) Pty Ltd (AU) 2014-05-14 EP claimed
WO-2013007698-A1 PHARMACEUTICAL COMPOSITION FOR NEUROLOGICAL DISORDERS GOSFORTH CENTRE (HOLDINGS) PTY LTD (AU) 2013-01-17 WO claimed
JP-2011529923-A 2011-12-15 JP claimed
CN-102170874-A Compositions and methods for treating psychiatric disorders GOSFORTH CT HOLDINGS PTY LTD 2011-08-31 CN claimed
US-20110207718-A1 COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC DISORDERS GOSFORTH CENTRE (HOLDINGS) PTY LTD. (AU) 2011-08-25 US claimed
EP-2331088-A1 COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC DISORDERS Gosforth Centre (Holdings) Pty Ltd (AU) 2011-06-15 EP claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1246797-B1 CYCLOPENTYL SULFONAMIDE DERIVATIVES LILLY CO ELI (US) 2008-07-23 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-6639107-B1 Potentiating glutamate receptor function ELI LILLY AND COMPANY 2003-10-28 US claimed
EP-1246797-A1 CYCLOPENTYL SULFONAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 2002-10-09 EP claimed
WO-2001042203-A1 CYCLOPENTYL SULFONAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 2001-06-14 WO claimed
WO-1997041878-A1 TREATMENT OF MOOD DISORDERS WITH A GROWTH HORMONE SECRETAGOGUE MERCK & CO., INC. (US) 1997-11-13 WO claimed
EP-0174342-B1 BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES UNIVERSITY OF FLORIDA (US) 1989-12-20 EP claimed
EP-0174342-A1 BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES. UNIV FLORIDA (US) 1986-03-19 EP claimed
WO-1985003937-A1 BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES UNIVERSITY OF FLORIDA (US) 1985-09-12 WO claimed