Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 20/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 11/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 11/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2934135 | 1.00 | CHRM3 (0.62) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Bromide SCHEMBL2797510 | 0.99 | CHRM3 (0.63) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Bromide SCHEMBL2797508 | 0.99 | CHRM3 (0.63) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL2927730 | 0.99 | CHRM3 (0.63) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL2927732 | 0.99 | CHRM3 (0.63) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Bromide SCHEMBL2798100 | 0.98 | CHRM3 (0.64) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Bromide SCHEMBL2798099 | 0.98 | CHRM3 (0.64) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL2927681 | 0.94 | CHRM3 (0.64) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL2927678 | 0.94 | CHRM3 (0.64) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Bromide SCHEMBL2799678 | 0.93 | CHRM3 (0.64) | CHRM3CHRM2CHRM1CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1811999-B1 | QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC M3 RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2010-09-15 | — | — | EP | claimed |