Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 20/20 | 0.83 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2930356 | 0.92 | GRIA2 (0.82) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL2929244 | 0.91 | GRIA2 (1.00) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL2934349 | 0.86 | GRIA2 (0.69) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL2932498 | 0.83 | GRIA2 (1.00) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL2929485 | 0.83 | GRIA2 (0.76) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL13297258 | 0.82 | GRIA2 (1.00) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL2930371 | 0.77 | GRIA2 (0.76) | GRIA2CYP1A2 | |
| SCHEMBL2932604 | 0.74 | GRIA2 (1.00) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL2936383 | 0.73 | GRIA2 (0.71) | GRIA2CYP1A2CYP2C19 | |
| SCHEMBL13297259 | 0.73 | GRIA2 (0.67) | GRIA2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786766-B1 | COMPOUNDS WHICH POTENTIATE GLUTAMATE RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LTD (GB) | 2010-09-22 | — | — | EP | claimed |
| EP-1786766-A1 | COMPOUNDS WHICH POTENTIATE GLUTAMATE RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-05-23 | — | — | EP | claimed |
| WO-2006015829-A1 | COMPOUNDS WHICH POTENTIATE GLUTAMATE RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2006-02-16 | — | — | WO | claimed |
| EP-1786766-B1 | COMPOUNDS WHICH POTENTIATE GLUTAMATE RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LTD (GB) | 2010-09-22 | — | — | EP | disclosed |
| EP-1786766-A1 | COMPOUNDS WHICH POTENTIATE GLUTAMATE RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006015829-A1 | COMPOUNDS WHICH POTENTIATE GLUTAMATE RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2006-02-16 | — | — | WO | disclosed |