Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.52 |
| ▸ | HPGD | P15428 | 8/20 | 0.52 |
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | AHR | P35869 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29432665 | 0.85 | AHR (0.61) | HSD17B10HPGDTSHRCASP1MAPK1 | |
| SCHEMBL4458352 | 0.85 | AHR (0.61) | HSD17B10HPGDTSHRCASP1MAPK1 | |
| SCHEMBL5948652 | 0.81 | HSD17B10 (0.54) | HSD17B10HPGDTSHRCASP1MAPK1 | |
| SCHEMBL5948180 | 0.81 | HSD17B10 (0.59) | HSD17B10HPGDTSHRCASP1MAPK1 | |
| SCHEMBL4449767 | 0.79 | AHR (0.61) | HSD17B10HPGDTSHRCASP1MAPK1 | |
| SCHEMBL29624835 | 0.79 | AHR (0.61) | HSD17B10HPGDTSHRCASP1MAPK1 | |
| SCHEMBL5948181 | 0.77 | HSD17B10 (0.50) | HSD17B10HPGDTSHRCASP1MAPK1 | |
| SCHEMBL11686234 | 0.77 | HSD17B10 (0.68) | HSD17B10HPGDTSHRCASP1MAPK1 | |
| SCHEMBL29386527 | 0.76 | HSD17B10 (0.61) | HSD17B10HPGDTSHRCASP1MAPK1 | |
| SCHEMBL5948395 | 0.76 | HSD17B10 (0.48) | HSD17B10HPGDTSHRCASP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |