Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2307489 | 0.98 | ESR1 (0.36) | ESR1ESR2 | |
| SCHEMBL4728017 | 0.98 | ESR1 (0.36) | ESR1ESR2 | |
| SCHEMBL8665314 | 0.80 | — | — | |
| SCHEMBL538153 | 0.78 | — | — | |
| SCHEMBL4729293 | 0.78 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL10500778 | 0.78 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL4730525 | 0.78 | ESR1 (0.36) | ESR1ESR2 | |
| SCHEMBL19578784 | 0.78 | CES1 (0.47) | ESR1ESR2 | |
| SCHEMBL7593649 | 0.78 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL7551581 | 0.78 | ESR1 (0.34) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771462-B1 | A PROCESS FOR THE PREPARATION OF 7-ALPHA-ALKYLATED 19-NORSTEROIDS | SICOR INC (US) | 2010-09-29 | — | — | EP | disclosed |
| US-7790910-B2 | such as fulvestrant | SICOR INC. (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090318721-A1 | Process for the preparation of 7alpha-alkylated 19-norsteroids | MACDONALD PETER LINDSAY | 2009-12-24 | — | — | US | disclosed |
| US-20090306417-A1 | Process for the preparation of 7alpha-alkylated 19-norsteroids | SICOR INC. | 2009-12-10 | — | — | US | disclosed |
| EP-1771462-A2 | A PROCESS FOR THE PREPARATION OF 7-ALPHA-ALKYLATED 19-NORSTEROIDS | Sicor Inc. (US) | 2007-04-11 | — | — | EP | disclosed |
| US-20060030552-A1 | Process for the preparation of 7alpha-alkylated 19-norsteroids | SICOR, INC. | 2006-02-09 | — | — | US | disclosed |
| WO-2006015081-A2 | A PROCESS FOR THE PREPARATION OF 7α-ALKYLATED 19-NORSTEROIDS | SICOR, INC. (US) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306417-A1 | Process for the preparation of 7alpha-alkylated 19-norsteroids | CYP19A1, CYP17A1, CYP4A11 | ESR1 97/4885ESR2 88/4885 |
| US-20060030552-A1 | Process for the preparation of 7alpha-alkylated 19-norsteroids | CYP19A1, CYP17A1, CYP4A11 | ESR1 97/4885ESR2 88/4885 |
| US-20090318721-A1 | Process for the preparation of 7alpha-alkylated 19-norsteroids | CYP19A1, CYP17A1, CYP4A11 | ESR1 97/4885ESR2 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.