SCHEMBL29346409

SCHEMBL29346409

O=C1CCCC2(CCNC2)C(=O)N1

nearest known ligand 0.79

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 6/20 0.79
OR51E2 Q9H255 1/20 0.32
FKBP5 Q13451 1/20 0.31
BACE1 P56817 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21496409 0.88 CRBN (1.00) CRBNBACE1
Hydrochloric Acid SCHEMBL21496432 0.86 CRBN (0.96) CRBNBACE1
SCHEMBL278215 0.79 CRBN (0.50) CRBNOR51E2FKBP5
SCHEMBL278367 0.79 CRBN (0.50) CRBNOR51E2FKBP5
SCHEMBL5393521 0.78 CRBN (0.68) CRBNBACE1
SCHEMBL29749828 0.78 CRBN (0.52) CRBNBACE1
SCHEMBL277887 0.77 CRBN (0.48) CRBNOR51E2FKBP5
SCHEMBL278221 0.77 CRBN (0.48) CRBNOR51E2FKBP5
SCHEMBL277992 0.77 CRBN (0.48) CRBNOR51E2FKBP5
Hydrochloric Acid SCHEMBL23067561 0.76 CRBN (0.66) CRBNBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-12-25 US disclosed
WO-2024150815-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR 田辺三菱製薬株式会社 2024-07-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR CRBN, CUL1, CBL CRBN 1/4885OR51E2 110/4885FKBP5 4754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.