Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 20/20 | 0.73 |
| ▸ | PRKCD | Q05655 | 19/20 | 0.73 |
| ▸ | LCK | P06239 | 3/20 | 0.67 |
| ▸ | LYN | P07948 | 3/20 | 0.67 |
| ▸ | PRKCH | P24723 | 3/20 | 0.67 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.67 |
| ▸ | SRC | P12931 | 2/20 | 0.67 |
| ▸ | PRKCB | P05771 | 2/20 | 0.67 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.57 |
| ▸ | IKBKB | O14920 | 1/20 | 0.57 |
| ▸ | CHUK | O15111 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.57 |
| ▸ | CDK1 | P06493 | 1/20 | 0.57 |
| ▸ | MET | P08581 | 1/20 | 0.57 |
| ▸ | HCK | P08631 | 1/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.57 |
| ▸ | CDK2 | P24941 | 1/20 | 0.57 |
| ▸ | AKT1 | P31749 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2929186 | 1.00 | PRKCQ (0.73) | PRKCQPRKCDLCKLYNPRKCH | |
| SCHEMBL2929372 | 0.88 | PRKCQ (0.73) | PRKCQPRKCDLCKLYNPRKCH | |
| SCHEMBL2936446 | 0.87 | PRKCQ (0.82) | PRKCQPRKCDLCKLYNPRKCH | |
| SCHEMBL2936448 | 0.87 | PRKCQ (0.82) | PRKCQPRKCDLCKLYNPRKCH | |
| SCHEMBL2934402 | 0.87 | PRKCQ (0.73) | PRKCQPRKCDLCKLYNPRKCH | |
| SCHEMBL2934403 | 0.87 | PRKCQ (0.73) | PRKCQPRKCDLCKLYNPRKCH | |
| SCHEMBL2933304 | 0.85 | PRKCQ (1.00) | PRKCQPRKCDLCKLYNPRKCH | |
| SCHEMBL2933300 | 0.85 | PRKCQ (1.00) | PRKCQPRKCDLCKLYNPRKCH | |
| SCHEMBL2992431 | 0.85 | PRKCQ (0.82) | PRKCQPRKCDLCKLYNPRKCH | |
| SCHEMBL2992433 | 0.85 | PRKCQ (0.82) | PRKCQPRKCDLCKLYNPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229377-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | Wyeth LLC (US) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009076602-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | WYETH (US) | 2009-06-18 | — | — | WO | disclosed |