SCHEMBL29347307

SCHEMBL29347307

CN(CCCCCC#Cc1cccc2c1n(C)c(=O)n2C1CCCC(=O)NC1=O)C(=O)OC(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 13/20 0.46
DDB1 Q16531 12/20 0.46
HDAC6 Q9UBN7 1/20 0.33
STAT3 P40763 1/20 0.33
IRAK4 Q9NWZ3 2/20 0.33
ADORA3 P0DMS8 1/20 0.32
CREBBP Q92793 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21071264 0.90 CRBN (0.48) CRBNDDB1HDAC6STAT3IRAK4
SCHEMBL21070389 0.90 CRBN (0.51) CRBNDDB1HDAC6STAT3IRAK4
SCHEMBL29347154 0.88 CRBN (0.41) CRBNDDB1HDAC6STAT3IRAK4
SCHEMBL21069509 0.87 DDB1 (0.60) CRBNDDB1IRAK4
SCHEMBL31730161 0.86 DDB1 (0.44) CRBNDDB1HDAC8
SCHEMBL21069679 0.86 DDB1 (0.47) CRBNDDB1IRAK4
SCHEMBL21071081 0.85 DDB1 (0.55) CRBNDDB1IRAK4
SCHEMBL31068610 0.85 CRBN (0.45) CRBNDDB1HDAC6STAT3IRAK4
SCHEMBL21069332 0.83 DDB1 (0.54) CRBNDDB1IRAK4
SCHEMBL25123321 0.82 CRBN (0.48) CRBNDDB1HDAC6STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-12-25 US disclosed
EP-4650348-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-11-19 EP disclosed
WO-2024150815-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR 田辺三菱製薬株式会社 2024-07-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR CRBN, CUL1, CBL CRBN 1/4885DDB1 2368/4885HDAC6 2391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.