SCHEMBL29347399

SCHEMBL29347399

O=C1CCCC2(CCN(C(=O)c3ccc4scnc4c3)C2)C(=O)N1

nearest known ligand 0.80

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 19/20 0.80
DDB1 Q16531 3/20 0.80
FASN P49327 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21496426 0.94 CRBN (0.85) CRBNDDB1
SCHEMBL23075759 0.89 CRBN (1.00) CRBNDDB1FASN
SCHEMBL23076100 0.89 CRBN (1.00) CRBNDDB1FASN
SCHEMBL23075751 0.89 CRBN (1.00) CRBNDDB1FASN
SCHEMBL21496464 0.86 CRBN (1.00) CRBNDDB1
SCHEMBL21484129 0.85 CRBN (1.00) CRBNDDB1FASN
SCHEMBL27013299 0.83 CRBN (0.81) CRBNDDB1FASN
SCHEMBL23075767 0.80 CRBN (0.71) CRBNDDB1FASN
SCHEMBL22932032 0.78 CRBN (0.67) CRBNDDB1FASN
SCHEMBL23067596 0.77 CRBN (1.00) CRBNDDB1FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4650348-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-11-19 EP disclosed
WO-2024150815-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR 田辺三菱製薬株式会社 2024-07-18 WO disclosed