SCHEMBL29348209

SCHEMBL29348209

CC(C)N1C(=O)OCC12CCC2

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 3/20 0.36
PIK3CD O00329 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25100292 0.96 IDH1 (0.39) IDH1PIK3CD
SCHEMBL21657462 0.92 IDH1 (0.33) IDH1
SCHEMBL25099327 0.84 CYP1A2 (0.31) IDH1
SCHEMBL22313305 0.82
SCHEMBL18650809 0.74 IDH1 (0.35) IDH1PIK3CD
SCHEMBL13379880 0.69 IDH1 (0.33) IDH1
SCHEMBL14376295 0.69 PIK3CD (0.41) IDH1PIK3CD
SCHEMBL18650807 0.67 PIK3CD (0.35) PIK3CD
SCHEMBL9551095 0.66 IDH1 (0.33) IDH1
SCHEMBL22052765 0.66 CYP2D6 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151547-A1 TARGETED DEGRADATION OF VAV1 MONTE ROSA THERAPEUTICS, INC. (US) 2024-07-18 WO disclosed