Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 8/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348288 | 0.93 | CRBN (0.44) | CRBNDDB1ALOX5APJAK2 | |
| SCHEMBL29348722 | 0.82 | CRBN (0.45) | CRBNDDB1JAK2 | |
| SCHEMBL31068277 | 0.81 | CRBN (0.46) | CRBNDDB1JAK2 | |
| SCHEMBL29348408 | 0.81 | CRBN (0.44) | CRBNDDB1ALOX5APJAK2 | |
| SCHEMBL29348377 | 0.80 | CRBN (0.44) | CRBNDDB1ALOX5APJAK2 | |
| SCHEMBL31068109 | 0.79 | CRBN (0.46) | CRBNDDB1JAK2 | |
| SCHEMBL29348437 | 0.79 | CRBN (0.46) | CRBNDDB1JAK2 | |
| SCHEMBL31068149 | 0.79 | CRBN (0.46) | CRBNDDB1JAK2 | |
| SCHEMBL29348439 | 0.79 | CRBN (0.46) | CRBNDDB1JAK2 | |
| SCHEMBL29348386 | 0.79 | CRBN (0.46) | CRBNDDB1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |