Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 6/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348394 | 0.88 | DDB1 (0.43) | DDB1CRBN | |
| SCHEMBL29348558 | 0.87 | CNR2 (0.53) | DDB1CRBNCNR2 | |
| SCHEMBL29348438 | 0.86 | DDB1 (0.40) | DDB1CRBNCNR2CMA1 | |
| SCHEMBL29348393 | 0.86 | CNR2 (0.42) | DDB1CRBNCNR2 | |
| SCHEMBL29348668 | 0.85 | DDB1 (0.40) | DDB1CRBNCNR2 | |
| SCHEMBL29348285 | 0.85 | DDB1 (0.41) | DDB1CRBNCNR2F10 | |
| SCHEMBL29348524 | 0.85 | CRBN (0.44) | DDB1CRBN | |
| SCHEMBL29348552 | 0.83 | CRBN (0.42) | DDB1CRBN | |
| SCHEMBL29348540 | 0.83 | DDB1 (0.38) | DDB1CRBNCNR2 | |
| SCHEMBL29348532 | 0.83 | DDB1 (0.40) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |