Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 12/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 12/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068275 | 1.00 | CNR2 (0.41) | CNR2DDB1CRBNCNR1BRD4 | |
| SCHEMBL29348599 | 0.96 | DDB1 (0.40) | CNR2DDB1CRBNCNR1BRD4 | |
| SCHEMBL31068292 | 0.96 | DDB1 (0.40) | CNR2DDB1CRBNCNR1BRD4 | |
| SCHEMBL31068179 | 0.95 | CNR2 (0.43) | CNR2DDB1CRBNCNR1BRD4 | |
| SCHEMBL29348604 | 0.95 | CNR2 (0.43) | CNR2DDB1CRBNCNR1BRD4 | |
| SCHEMBL29348576 | 0.89 | DDB1 (0.38) | CNR2DDB1CRBNCNR1BRD4 | |
| SCHEMBL31068103 | 0.89 | DDB1 (0.38) | CNR2DDB1CRBNCNR1BRD4 | |
| SCHEMBL29348574 | 0.88 | DDB1 (0.38) | CNR2DDB1CRBNCNR1BRD4 | |
| SCHEMBL31068246 | 0.88 | DDB1 (0.38) | CNR2DDB1CRBNCNR1BRD4 | |
| SCHEMBL29348664 | 0.86 | DDB1 (0.40) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |