Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348775 | 1.00 | MEN1 (0.40) | MEN1KMT2AATMRXFP1IDH1 | |
| SCHEMBL29348772 | 1.00 | MEN1 (0.40) | MEN1KMT2AATMRXFP1IDH1 | |
| SCHEMBL8585033 | 0.82 | NOTUM (0.44) | MEN1KMT2AIDH1ALDH1A1MAPT | |
| SCHEMBL6883044 | 0.82 | NOTUM (0.44) | MEN1KMT2AIDH1ALDH1A1MAPT | |
| SCHEMBL6871051 | 0.82 | NOTUM (0.44) | MEN1KMT2AIDH1ALDH1A1MAPT | |
| SCHEMBL850457 | 0.80 | TSHR (0.45) | IDH1ALDH1A1TSHRMAPTLMNA | |
| SCHEMBL2365947 | 0.79 | USP2 (0.46) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL2365942 | 0.79 | USP2 (0.46) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL29348974 | 0.77 | MEN1 (0.38) | MEN1KMT2AATMRXFP1CYP3A4 | |
| SCHEMBL5429899 | 0.74 | IDH1 (0.51) | MEN1KMT2AIDH1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |