Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 19/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 19/20 | 0.40 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | IL1B | P01584 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068097 | 1.00 | DDB1 (0.40) | DDB1CRBNIKZF3ALDH1A1CHRM2 | |
| SCHEMBL29348559 | 0.98 | DDB1 (0.40) | DDB1CRBNIKZF3ALDH1A1CHRM2 | |
| SCHEMBL29348664 | 0.94 | DDB1 (0.40) | DDB1CRBNIKZF3ALDH1A1CHRM2 | |
| SCHEMBL29348624 | 0.94 | DDB1 (0.41) | DDB1CRBNIKZF3ALDH1A1CHRM2 | |
| SCHEMBL29348617 | 0.93 | CRBN (0.37) | DDB1CRBNIKZF3ALDH1A1CHRM2 | |
| SCHEMBL31068189 | 0.90 | DDB1 (0.40) | DDB1CRBNIKZF3ALDH1A1CHRM2 | |
| SCHEMBL31068119 | 0.89 | DDB1 (0.41) | DDB1CRBNIKZF3ALDH1A1CHRM2 | |
| SCHEMBL29348910 | 0.89 | DDB1 (0.41) | DDB1CRBNIKZF3ALDH1A1CHRM2 | |
| SCHEMBL29348572 | 0.87 | CRBN (0.38) | DDB1CRBNIKZF3ALDH1A1CHRM2 | |
| SCHEMBL29348567 | 0.87 | CRBN (0.38) | DDB1CRBNIKZF3ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |