Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 19/20 | 0.64 |
| ▸ | CRBN | Q96SW2 | 19/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068300 | 1.00 | DDB1 (0.64) | DDB1CRBNPOLB | |
| SCHEMBL29348755 | 0.82 | DDB1 (0.56) | DDB1CRBN | |
| SCHEMBL31068264 | 0.82 | DDB1 (0.56) | DDB1CRBN | |
| SCHEMBL31068105 | 0.82 | DDB1 (0.56) | DDB1CRBN | |
| SCHEMBL29348330 | 0.82 | DDB1 (0.56) | DDB1CRBN | |
| SCHEMBL30139708 | 0.81 | DDB1 (0.58) | DDB1CRBNPOLB | |
| SCHEMBL31637558 | 0.79 | DDB1 (0.52) | DDB1CRBN | |
| SCHEMBL459725 | 0.78 | DDB1 (1.00) | DDB1CRBN | |
| SCHEMBL29322273 | 0.74 | DDB1 (0.50) | DDB1CRBN | |
| SCHEMBL31726967 | 0.74 | DDB1 (0.47) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |