SCHEMBL2935000

SCHEMBL2935000

CC(C)C(C)(C)[SiH2]OCCCCCCCCCBr.[MgH2]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10753644 1.00
SCHEMBL6544649 0.98
SCHEMBL9862482 0.98
SCHEMBL9862631 0.98
SCHEMBL9862573 0.98
SCHEMBL21220134 0.90
SCHEMBL1226347 0.82
SCHEMBL9517443 0.79
SCHEMBL28102478 0.79
SCHEMBL28102366 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1771462-B1 A PROCESS FOR THE PREPARATION OF 7-ALPHA-ALKYLATED 19-NORSTEROIDS SICOR INC (US) 2010-09-29 EP disclosed
US-7790910-B2 such as fulvestrant SICOR INC. (US) 2010-09-07 US disclosed
US-20090318721-A1 Process for the preparation of 7alpha-alkylated 19-norsteroids MACDONALD PETER LINDSAY 2009-12-24 US disclosed
US-20090306417-A1 Process for the preparation of 7alpha-alkylated 19-norsteroids SICOR INC. 2009-12-10 US disclosed
EP-1771462-A2 A PROCESS FOR THE PREPARATION OF 7-ALPHA-ALKYLATED 19-NORSTEROIDS Sicor Inc. (US) 2007-04-11 EP disclosed
US-20060030552-A1 Process for the preparation of 7alpha-alkylated 19-norsteroids SICOR, INC. 2006-02-09 US disclosed
WO-2006015081-A2 A PROCESS FOR THE PREPARATION OF 7α-ALKYLATED 19-NORSTEROIDS SICOR, INC. (US) 2006-02-09 WO disclosed