Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TOP2A | P11388 | 2/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28691169 | 1.00 | KDM4E (0.64) | KDM4EALDH1A1PIK3CGLMNAHPGD | |
| SCHEMBL28933214 | 0.90 | KDM4E (0.73) | KDM4EALDH1A1PIK3CGLMNAHPGD | |
| SCHEMBL28933213 | 0.90 | KDM4E (0.73) | KDM4EALDH1A1PIK3CGLMNAHPGD | |
| SCHEMBL28419280 | 0.90 | KDM4E (0.64) | KDM4EALDH1A1PIK3CGLMNAHPGD | |
| SCHEMBL28572470 | 0.90 | KDM4E (0.64) | KDM4EALDH1A1PIK3CGLMNAHPGD | |
| SCHEMBL30615709 | 0.90 | KDM4E (0.64) | KDM4EALDH1A1PIK3CGLMNAHPGD | |
| SCHEMBL28706846 | 0.87 | KDM4E (0.70) | KDM4EALDH1A1PIK3CGLMNAHPGD | |
| SCHEMBL28706845 | 0.87 | KDM4E (0.70) | KDM4EALDH1A1PIK3CGLMNAHPGD | |
| SCHEMBL28690424 | 0.86 | KDM4E (0.69) | KDM4EALDH1A1PIK3CGLMNAHPGD | |
| SCHEMBL28690425 | 0.86 | KDM4E (0.69) | KDM4EALDH1A1PIK3CGLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111646937-B | Propenone derivative of N-acetyl ciprofloxacin and preparation method and application thereof | 河南大学 | 2022-01-21 | — | — | CN | disclosed |