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SCHEMBL29350600

SCHEMBL29350600

CCCCCCCC(=O)N[C@H](C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC)NC1=O)[C@@H](C)O

nearest known ligand 0.84

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 3/20 0.84
▸ RCOR1 Q9UKL0 2/20 0.84
▸ PSMB5 P28074 15/20 0.43
▸ PSMB2 P49721 9/20 0.43
▸ SLC40A1 Q9NP59 1/20 0.42
▸ SSTR2 P30874 1/20 0.40
▸ SSTR4 P31391 1/20 0.40
▸ SSTR5 P35346 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21476992 0.96 KDM1A (0.85) KDM1ARCOR1PSMB5PSMB2SLC40A1
Polymyxin B4 SCHEMBL21476967 0.96 KDM1A (0.91) KDM1ARCOR1PSMB5PSMB2SLC40A1
Polymyxin B5 SCHEMBL21258460 0.96 KDM1A (0.91) KDM1ARCOR1PSMB5PSMB2SLC40A1
Polymyxin B3 SCHEMBL21474115 0.96 KDM1A (0.91) KDM1ARCOR1PSMB5PSMB2SLC40A1
SCHEMBL16426325 0.95 KDM1A (0.90) KDM1ARCOR1PSMB5PSMB2SSTR2
SCHEMBL21335094 0.95 KDM1A (0.90) KDM1ARCOR1PSMB5PSMB2SSTR2
SCHEMBL21335230 0.95 KDM1A (0.90) KDM1ARCOR1PSMB5PSMB2SSTR2
SCHEMBL21335093 0.95 KDM1A (0.90) KDM1ARCOR1PSMB5PSMB2SSTR2
SCHEMBL16425729 0.95 KDM1A (0.90) KDM1ARCOR1PSMB5PSMB2SSTR2
SCHEMBL16426302 0.95 KDM1A (0.90) KDM1ARCOR1PSMB5PSMB2SSTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113039199-B Activin/bone morphogenic protein 7 chimeras superactive SAB704 and SAB715 and NAB704, NAB715 and NAB204 as their noggin-sensitized variants OSR控股有限公司 2025-03-14 — — CN disclosed
CN-113039199-B Activin/bone morphogenic protein 7 chimeras superactive SAB704 and SAB715 and NAB704, NAB715 and NAB204 as their noggin-sensitized variants OSR控股有限公司 2025-03-14 — — CN disclosed
EP-3880695-A4 ACTIVIN/BMP7 CHIMERAS: SUPER-ACTIVE SAB704 AND SAB715, AND THEIR RESPECTIVE NOGGIN-SENSITIZED VARIANTS, NAB704 AND NAB715; AND NAB204 Joint Center For Biosciences (KR) 2022-01-19 — — EP disclosed
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