Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 18/20 | 0.73 |
| ▸ | PRKCD | Q05655 | 15/20 | 0.73 |
| ▸ | CDK1 | P06493 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PRKCH | P24723 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2935442 | 0.87 | PRKCQ (0.69) | PRKCQPRKCDPRKCHPRKCELYN | |
| SCHEMBL2935439 | 0.87 | PRKCQ (0.69) | PRKCQPRKCDPRKCHPRKCELYN | |
| SCHEMBL2936220 | 0.84 | PRKCQ (1.00) | PRKCQPRKCDCDK1KDRMAOB | |
| SCHEMBL2933194 | 0.83 | PRKCQ (0.69) | PRKCQPRKCDPRKCHPRKCELYN | |
| SCHEMBL2933197 | 0.83 | PRKCQ (0.69) | PRKCQPRKCDPRKCHPRKCELYN | |
| SCHEMBL1145403 | 0.79 | PRKCQ (0.58) | PRKCQPRKCDCDK1KDRPRKCH | |
| SCHEMBL2933853 | 0.74 | PRKCQ (0.74) | PRKCQPRKCDPRKCHPRKCE | |
| SCHEMBL5513217 | 0.74 | PRKCQ (1.00) | PRKCQPRKCDCDK1KDRPRKCH | |
| SCHEMBL1145797 | 0.73 | PRKCQ (0.56) | PRKCQPRKCDCDK1KDRPRKCH | |
| SCHEMBL2935616 | 0.73 | PRKCQ (0.59) | PRKCQPRKCDPRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229377-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | Wyeth LLC (US) | 2010-09-22 | — | — | EP | claimed |
| WO-2009076602-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | WYETH (US) | 2009-06-18 | — | — | WO | claimed |
| EP-2229377-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | Wyeth LLC (US) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009076602-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | WYETH (US) | 2009-06-18 | — | — | WO | disclosed |