Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 17/20 | 0.63 |
| ▸ | CSNK2A1 | P68400 | 10/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 8/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.55 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.54 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.54 |
| ▸ | HIPK1 | Q86Z02 | 2/20 | 0.54 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.54 |
| ▸ | HIPK3 | Q9H422 | 2/20 | 0.54 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.54 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.52 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.52 |
| ▸ | DAPK2 | Q9UIK4 | 1/20 | 0.52 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19742591 | 0.94 | CSNK2A2 (0.71) | CSNK2A2CSNK2A1CSNK2BKCNH2HIPK2 | |
| Trifluoroacetic Acid SCHEMBL29355545 | 0.93 | CSNK2A2 (0.61) | CSNK2A2CSNK2A1CSNK2BKCNH2HIPK2 | |
| Trifluoroacetic Acid SCHEMBL29355704 | 0.91 | CSNK2A2 (0.59) | CSNK2A2CSNK2A1CSNK2BKCNH2HIPK2 | |
| Trifluoroacetic Acid SCHEMBL29354507 | 0.89 | CSNK2A2 (0.64) | CSNK2A2CSNK2A1CSNK2BKCNH2HIPK2 | |
| Trifluoroacetic Acid SCHEMBL29352566 | 0.88 | CSNK2A2 (0.62) | CSNK2A2CSNK2A1CSNK2BKCNH2HIPK2 | |
| Trifluoroacetic Acid SCHEMBL29352638 | 0.88 | CSNK2A2 (0.62) | CSNK2A2CSNK2A1CSNK2BKCNH2HIPK2 | |
| Trifluoroacetic Acid SCHEMBL29355671 | 0.88 | CSNK2A2 (0.61) | CSNK2A2CSNK2A1CSNK2BKCNH2HIPK2 | |
| Trifluoroacetic Acid SCHEMBL29354134 | 0.87 | CSNK2A2 (0.60) | CSNK2A2CSNK2A1CSNK2BKCNH2HIPK2 | |
| Trifluoroacetic Acid SCHEMBL29355485 | 0.86 | CSNK2A2 (0.67) | CSNK2A2CSNK2A1CSNK2BKCNH2HIPK2 | |
| Trifluoroacetic Acid SCHEMBL29355859 | 0.86 | CSNK2A2 (0.67) | CSNK2A2CSNK2A1CSNK2BKCNH2HIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3474855-B1 | CK2 INHIBITORS, COMPOSITIONS AND METHODS THEREOF | POLARIS PHARMACEUTICALS INC (US) | 2022-01-26 | — | — | EP | claimed |
| EP-3474855-B1 | CK2 INHIBITORS, COMPOSITIONS AND METHODS THEREOF | POLARIS PHARMACEUTICALS INC (US) | 2022-01-26 | — | — | EP | disclosed |