Leiocarpin

Leiocarpin

SCHEMBL29352437

CC1(C)C=Cc2c(ccc3c2OCC2c4cc5c(cc4OC32)OCO5)O1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.59
MAOA P21397 2/20 0.53
MAOB P27338 2/20 0.53
PTPN1 P18031 6/20 0.53
CYP3A4 P08684 4/20 0.49
MAPT P10636 3/20 0.49
MAPK1 P28482 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
HSP90AA1 P07900 3/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
TTR P02766 1/20 0.45
TYR P14679 1/20 0.45
ODC1 P11926 1/20 0.42
TP53 P04637 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Shinpterocarpin SCHEMBL30001940 0.85 MGAM (0.77) MGAMMAOAMAOBPTPN1CYP3A4
Shinpterocarpin SCHEMBL29377666 0.85 MGAM (0.77) MGAMMAOAMAOBPTPN1CYP3A4
SCHEMBL13794192 0.83 MGAM (0.59) MGAMMAOAMAOBPTPN1CYP3A4
SCHEMBL30549402 0.75 MGAM (0.60) MGAMPTPN1CYP3A4MAPK1HSP90AA1
SCHEMBL30549401 0.75 MGAM (0.60) MGAMPTPN1CYP3A4MAPK1HSP90AA1
Phaseolin SCHEMBL29351585 0.74 MGAM (1.00) MGAMMAOAMAOBPTPN1CYP3A4
Phaseolin SCHEMBL33736 0.74 MGAM (1.00) MGAMMAOAMAOBPTPN1CYP3A4
Phaseolin SCHEMBL29929606 0.74 MGAM (1.00) MGAMMAOAMAOBPTPN1CYP3A4
Phaseolin SCHEMBL33735 0.74 MGAM (1.00) MGAMMAOAMAOBPTPN1CYP3A4
Phaseolin SCHEMBL28856370 0.73 MGAM (0.98) MGAMMAOAMAOBPTPN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112272519-B Single unit body encapsulation via pickering emulsions for biopesticides 以色列国家农业部、农村发展农业研究组织 2023-01-06 CN claimed
EP-3943085-A2 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH Zurich (CH) 2022-01-26 EP claimed
CN-112272519-B Single unit body encapsulation via pickering emulsions for biopesticides 以色列国家农业部、农村发展农业研究组织 2023-01-06 CN disclosed
CN-115568477-A Composite medicament for preventing and treating sesame wilt and application thereof 江西省农业科学院植物保护研究所 2023-01-06 CN disclosed
CN-115487226-A A topical natural bactericide pharmaceutical composition 云南中医药大学 2022-12-20 CN disclosed
CN-109153696-B Method for purifying antifungal compounds and exopolysaccharides from microbial cell cultures 拜耳作物科学有限合伙公司 2022-10-21 CN disclosed
CN-114752506-A Bacterial strain for controlling underground pests and application thereof 云南绿戎生物产业开发股份有限公司 2022-07-15 CN disclosed
US-PP34004-P2 Heliotropium plant named ‘WNHPAULAV’ WINGEN, LLC (US) 2022-03-08 US disclosed
EP-3943085-A2 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH Zurich (CH) 2022-01-26 EP disclosed
CN-113957103-A Method for producing methacrylic acid and/or ester thereof 三菱化学株式会社 2022-01-21 CN disclosed