Galanin

Galanin

SCHEMBL29352997

CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 14/20 0.67
▸ GCGR P47871 4/20 0.67
▸ NPY1R P25929 1/20 0.66
▸ NPY2R P49146 1/20 0.66
▸ NPY4R P50391 1/20 0.66
▸ NPY5R Q15761 1/20 0.66
▸ GIPR P48546 1/20 0.65
▸ CCKBR P32239 2/20 0.65
▸ CALCA P06881 2/20 0.65
▸ KEAP1 Q14145 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30932197 0.94 GLP1R (0.71) GLP1RGCGRNPY1RNPY2RNPY4R
SCHEMBL30523133 0.94 GLP1R (0.71) GLP1RGCGRNPY1RNPY2RNPY4R
SCHEMBL30495753 0.94 NPY1R (0.70) GLP1RGCGRNPY1RNPY2RNPY4R
SCHEMBL30598194 0.90 NPY1R (0.71) GLP1RGCGRNPY1RNPY2RNPY4R
SCHEMBL30598153 0.90 NPY1R (0.70) GLP1RGCGRNPY1RNPY2RNPY4R
SCHEMBL30598171 0.90 GLP1R (0.71) GLP1RGCGRNPY1RNPY2RNPY4R
SCHEMBL30598183 0.90 NPY1R (0.70) GLP1RGCGRNPY1RNPY2RNPY4R
SCHEMBL30658239 0.90 NPY1R (0.69) GLP1RGCGRNPY1RNPY2RNPY4R
SCHEMBL30598150 0.89 NPY1R (0.69) GLP1RGCGRNPY1RNPY2RNPY4R
SCHEMBL31182715 0.89 NPY1R (0.70) GLP1RGCGRNPY1RNPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2347 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624037-B2 Method of treating agitation, aggressive behavior, and impulse control disorder INTRA-CELLULAR THERAPIES, INC. (US) 2026-05-12 — — US claimed
US-12624036-B2 Method of treating post-traumatic stress disorder INTRA-CELLULAR THERAPIES, INC. (US) 2026-05-12 — — US claimed
EP-4732908-A2 CANCER TREATMENT USING COMBINATIONS OF ERK AND RAF INHIBITORS Biomed Valley Discoveries, Inc. (US) 2026-04-29 — — EP claimed
EP-3532092-B1 IMMUNOGLOBULINS AND USES THEREOF JANSSEN PHARMACEUTICA NV (BE) 2026-04-29 — — EP claimed
US-20260110698-A1 METHODS FOR QUANTIFYING FRATAXIN ACTIVITY LARIMAR THERAPEUTICS INC (US) 2026-04-23 — — US claimed
EP-4724044-A2 TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS WITH EXTRACELLULAR VESICLE COMPOSITION Direct Biologics, LLC (US) 2026-04-15 — — EP claimed
EP-4724043-A2 TREATMENT OF COMPLEX REGIONAL PAIN SYNDROME WITH EXTRACELLULAR VESICLE COMPOSITION Direct Biologics, LLC (US) 2026-04-15 — — EP claimed
EP-4712959-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING 2,3,4,5-TETRAHYDRO-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES AND THE USE THEREOF Mirum Pharmaceuticals, Inc. (US) 2026-03-25 — — EP claimed
EP-4698662-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2026-02-25 — — EP claimed
EP-3768271-B1 ORGANIC COMPOUNDS INTRA CELLULAR THERAPIES INC (US) 2026-02-18 — — EP claimed
US-20220160728-A1 GENE THERAPY METHODS HOMOLOGY MEDICINES INC (US) 2022-05-26 — — US claimed
US-20220160895-A1 GENE THERAPY METHODS HOMOLOGY MEDICINES, INC. 2022-05-26 — — US claimed
WO-2022099301-A1 IMPROVED GENE THERAPY METHODS HOMOLOGY MEDICINES, INC. (US) 2022-05-12 — — WO claimed
WO-2022099299-A1 IMPROVED GENE THERAPY METHODS HOMOLOGY MEDICINES, INC. (US) 2022-05-12 — — WO claimed
US-20220133839-A1 PEPTIDE ANALOGUES WITH BRANCHED AMINO ACID PROBE(S) TXP PHARMA GMBH (CH) 2022-05-05 — — US claimed
CN-108348570-B SPEXIN-based galanin type 2 receptor agonists and uses thereof 纽洛可科学有限公司 2022-05-03 — — CN claimed
EP-3984537-A1 CANCER TREATMENTS USING COMBINATIONS OF TYPE 2 MEK AND ERK INHIBITORS Biomed Valley Discoveries, Inc. (US) 2022-04-20 — — EP claimed
CN-114306870-A Device and method for regulating galanin level and neurotransmitter concentration in brain 李彤 2022-04-12 — — CN claimed
US-20220089821-A1 HYDROGEL-ENCAPSULATED BETA CELLS, BETA-CELL ENCAPSULATION PROCESS, AND USES THEREOF UNIVERSITY OF WYOMING 2022-03-24 — — US claimed
CN-114181315-A Endosome escape peptide and application thereof 清华大学 2022-03-15 — — CN claimed
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