SCHEMBL29353046

SCHEMBL29353046

c1ccc2c(-c3cnn4cc(-c5ccc(N6CCNCC6)cc5)cnc34)ccnc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACVR1 Q04771 15/20 1.00
ACVR1B P36896 14/20 1.00
BMPR1A P36894 14/20 1.00
ACVRL1 P37023 14/20 1.00
BMPR1B O00238 12/20 1.00
KDR P35968 4/20 1.00
TGFBR1 P36897 4/20 1.00
TGFBR2 P37173 4/20 1.00
BMPR2 Q13873 4/20 1.00
PRKAB1 Q9Y478 4/20 1.00
BMP4 P12644 4/20 1.00
RIPK2 O43353 1/20 1.00
ACVR2A P27037 1/20 1.00
ACVR2B Q13705 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL456393 1.00 ACVR1 (1.00) ACVR1ACVR1BBMPR1AACVRL1BMPR1B
Hydrochloric Acid SCHEMBL22462135 0.99 ACVR1 (0.98) ACVR1ACVR1BBMPR1AACVRL1BMPR1B
Hydrochloric Acid SCHEMBL29634729 0.99 ACVR1 (0.98) ACVR1ACVR1BBMPR1AACVRL1BMPR1B
Hydrochloric Acid SCHEMBL2059683 0.99 ACVR1 (0.98) ACVR1ACVR1BBMPR1AACVRL1BMPR1B
Hydrochloric Acid SCHEMBL29373122 0.99 ACVR1 (0.98) ACVR1ACVR1BBMPR1AACVRL1BMPR1B
Hypochlorous Acid SCHEMBL26968209 0.97 ACVR1B (0.94) ACVR1ACVR1BBMPR1AACVRL1BMPR1B
SCHEMBL24908393 0.94 ACVR1B (0.89) ACVR1ACVR1BBMPR1AACVRL1BMPR1B
SCHEMBL29391702 0.93 ACVR1 (1.00) ACVR1ACVR1BBMPR1AACVRL1BMPR1B
SCHEMBL16025991 0.93 ACVR1 (1.00) ACVR1ACVR1BBMPR1AACVRL1BMPR1B
Hydrochloric Acid SCHEMBL30388107 0.92 ACVR1 (0.98) ACVR1ACVR1BBMPR1AACVRL1BMPR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3255 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3594323-B1 METHODS AND COMPOSITIONS FOR GENERATING PANCREATIC PROGENITORS AND FUNCTIONAL BETA CELLS FROM HPSCS UNIV HEALTH NETWORK (CA) 2026-05-27 EP claimed
EP-4747363-A1 NEURAL DIFFERENTIATION FROM PLURIPOTENT CELLS Treefrog Therapeutics (FR) 2026-05-27 EP claimed
CN-122055439-A Methods for differentiating dopaminergic neurons from stem cells 艾斯本神经科学公司 2026-05-15 CN claimed
CN-122038274-A Method for inducing differentiation and maturation of alveolar organoids and application thereof 广州国家实验室 2026-05-15 CN claimed
CN-122038284-A Method for inducing differentiation of anterior foregut endoderm cells to form lung progenitor cells and application thereof 广州国家实验室 2026-05-15 CN claimed
CN-122038285-A Kit and method for constructing human bone organ by using pluripotent stem cells 广东医科大学附属医院 2026-05-15 CN claimed
US-20260125650-A1 METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES TRAILHEAD BIOSYSTEMS INC (US) 2026-05-07 US claimed
US-20260124247-A1 METHODS FOR MAKING AUDITORY PROGENITOR CELLS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-07 US claimed
WO-2026090278-A1 SYSTEMS, COMPOSITIONS, AND METHODS FOR CONVERTING A CELL TO A RETINAL PHOTORECEPTOR INDUCED NEURON (PR-IN) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-04-30 WO claimed
US-20260117184-A1 SYSTEM AND METHOD TO DIRECT THE DIFFERENTIATION OF PLURIPOTENT STEM CELL-DERIVED ODONTOBLASTS UNIVERSITY OF WASHINGTON (US) 2026-04-30 US claimed
WO-2022037570-A1 EXPANSION CULTURE MEDIUM AND CULTURE METHOD FOR NEURAL CELLS 中国科学院动物研究所 2022-02-24 WO claimed
EP-3303564-B1 METHODS OF IN VITRO DIFFERENTIATION OF MIDBRAIN DOPAMINE (MDA) NEURONS MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-02-23 EP claimed
CN-113388580-B Method for inducing adipose-derived stem cells to differentiate into functional dopaminergic neurons and application 中国医学科学院医学实验动物研究所 2022-02-18 CN claimed
CN-114072163-A New material for healing skin wound and preventing scar 芝加哥大学 2022-02-18 CN claimed
CN-111500526-B Composition for in-vitro culture of primary mouse corneal epithelial cells and application thereof 厦门大学 2022-02-18 CN claimed
EP-3954758-A1 METHOD FOR INDUCING DIRECT REPROGRAMMING OF URINE CELL INTO RENAL PROGENITOR CELL AND PHARMACEUTICAL COMPOSITION COMPRISING RENAL PROGENITOR CELL REPROGRAMMED BY SAME METHOD FOR PREVENTING OR TREATING RENAL CELL INJURY DISEASE Korea University Research and Business Foundation (KR) 2022-02-16 EP claimed
EP-3947651-A1 METHOD FOR OBTAINING OR MAINTAINING ABCG2-POSITIVE CORNEAL LIMBAL STEM CELLS Stemsight Oy (FI) 2022-02-09 EP claimed
WO-2022026932-A2 DIFFERENTIATION OF PANCREATIC ENDOCRINE CELLS VERTEX PHARMACEUTICALS INCORPORATED (US) 2022-02-03 WO claimed
WO-2022022624-A1 METHOD FOR PRODUCING CARDIOMYOCYTES BY MEANS OF REPROGRAMMING 南京昕瑞再生医药科技有限公司 2022-02-03 WO claimed
WO-2022020798-A1 METHODS OF DIFFERENTIATING NEURONS AND IDENTIFICATION OF DISEASE PHENOTYPES THEREOF THE SCRIPPS RESEARCH INSTITUTE (US) 2022-01-27 WO claimed