Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lansoprazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A known ✓ | P20648 | 4/20 | 0.61 |
| ▸ | ATP4B known ✓ | P51164 | 4/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | WDR5 | P61964 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ENGASE | Q8NFI3 | 3/20 | 0.61 |
| ▸ | SARM1 | Q6SZW1 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | ATP1A1 | P05023 | 3/20 | 0.61 |
| ▸ | ATP1B1 | P05026 | 3/20 | 0.61 |
| ▸ | ATP1A3 | P13637 | 3/20 | 0.61 |
| ▸ | ATP1B2 | P14415 | 3/20 | 0.61 |
| ▸ | ATP1A2 | P50993 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dexlansoprazole SCHEMBL29950208 | 1.00 | CYP2C9 (0.63) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 | |
| Dexlansoprazole SCHEMBL29353881 | 1.00 | CYP2C9 (0.63) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 | |
| Dexlansoprazole SCHEMBL29598842 | 1.00 | CYP2C9 (0.63) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 | |
| Lansoprazole SCHEMBL8597994 | 1.00 | CYP2C9 (0.63) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 | |
| Lansoprazole SCHEMBL22366 | 1.00 | CYP2C9 (0.63) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 | |
| Lansoprazole SCHEMBL29358567 | 1.00 | CYP2C9 (0.63) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 | |
| Dexlansoprazole SCHEMBL29750802 | 1.00 | CYP2C9 (0.63) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 | |
| Lansoprazole SCHEMBL1559598 | 1.00 | CYP2C9 (0.63) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 | |
| Dexlansoprazole SCHEMBL44975 | 1.00 | CYP2C9 (0.63) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 | |
| Lansoprazole SCHEMBL22365 | 1.00 | CYP2C9 (0.63) | CYP2C9NPC1RAB9ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 356 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119419680-A | Cover plate with graphene heating film | 江苏默顿电气有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-222190180-U | Cover plate with self-adaptive screen brightness adjusting structure | 信利光电股份有限公司 | 2024-12-17 | — | — | CN | claimed |
| US-20240390364-A1 | Novel Pyridine Compositions and their use in methods for preventing or treating diseases, disorders and conditions | REID CHRISTOPHER BRIAN (US) | 2024-11-28 | — | — | US | claimed |
| CN-220873198-U | Cover plate structure with peep-proof function | 信利光电股份有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-220775249-U | MPP cable protection tube | 江苏铭鼎新材料科技有限公司 | 2024-04-12 | — | — | CN | claimed |
| WO-2024026463-A1 | COMPOSITION FOR NASAL DELIVERY OF AN ACTIVE COMPOUND | HAPPY HEALING INC. (US) | 2024-02-01 | — | — | WO | claimed |
| CN-220381309-U | Cover plate with polarizing function and display device | 信利光电股份有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-117239319-A | Novel cover plate structure with partition plate | 中山市润烨新能源科技有限公司 | 2023-12-15 | — | — | CN | claimed |
| CN-219972977-U | Parking apron with drainage function | 济南驰昊电力科技有限公司 | 2023-11-07 | — | — | CN | claimed |
| WO-2023193244-A1 | SUPRAMOLECULAR SELF-ASSEMBLY SYSTEM | 北京睿创康泰医药研究院有限公司 | 2023-10-12 | — | — | WO | claimed |
| CN-114075703-B | Lower leather collar pin with tensioning mechanism | 山西贝斯特机械制造有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-218370150-U | Self-made horizontal transportation device with sliding cover plate | 中国建筑第八工程局有限公司 | 2023-01-24 | — | — | CN | claimed |
| CN-115559932-A | Cover plate extension type low-noise pump impeller with splitter blades | 江苏大学镇江流体工程装备技术研究院 | 2023-01-03 | — | — | CN | claimed |
| CN-115319203-A | Cover plate type casting surface treatment device with stress balance function | 江苏中科云控智能工业装备有限公司 | 2022-11-11 | — | — | CN | claimed |
| CN-114881186-A | Industrial product positioning RFID reader-writer and use method thereof | 苏州工业园区斯佰瑞特电子有限公司 | 2022-08-09 | — | — | CN | claimed |
| CN-114865181-A | Cover plate assembly with battery aluminum switching piece | 浙江锦泰电子有限公司 | 2022-08-05 | — | — | CN | claimed |
| EP-3426657-B1 | 2 AMINO N [7 METHOXY 2, 3-DIHYDROIMIDAZO-[1, 2-C]QUINAZOLIN-5-YL]PYRIMIDINE 5 CARBOXAMIDES | Bayer Pharma AG (DE) | 2022-07-13 | — | — | EP | claimed |
| CN-114075703-A | Lower leather collar pin with tensioning mechanism | 山西贝斯特机械制造有限公司 | 2022-02-22 | — | — | CN | claimed |
| WO-2026107208-A1 | COMPOSITIONS AND METHODS FOR TREATING MICROBIAL INFECTIONS | THE METHODIST HOSPITAL (US) | 2026-05-21 | — | — | WO | disclosed |
| CN-215598799-U | Sewage treatment sampling device | 中国市政工程西南设计研究总院有限公司 | 2022-01-21 | — | — | CN | disclosed |