SCHEMBL2935402

SCHEMBL2935402

CCCC[N+](CCCC)(CCCC)CCCC#N

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.62
SLC22A1 O15245 3/20 0.60
SLC22A2 O15244 1/20 0.52
ALDH1A1 P00352 1/20 0.48
TP53 P04637 1/20 0.48
CYP3A4 P08684 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HIF1A Q16665 1/20 0.48
HSD17B10 Q99714 1/20 0.48
DNM1 Q05193 6/20 0.44
APAF1 O14727 1/20 0.37
HSP90AA1 P07900 1/20 0.37
RAD52 P43351 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3629654 0.93 TSHR (0.59) TSHRSLC22A1SLC22A2ALDH1A1TP53
Tetrabuthylammonium SCHEMBL28129614 0.91 TSHR (0.56) TSHRSLC22A1SLC22A2ALDH1A1TP53
Hydrogen Sulfide SCHEMBL28156175 0.84
SCHEMBL3402684 0.83 SLC22A1 (0.62) TSHRSLC22A1SLC22A2ALDH1A1TP53
SCHEMBL3395180 0.83 SLC22A1 (0.62) TSHRSLC22A1SLC22A2ALDH1A1TP53
SCHEMBL10256740 0.83 TSHR (0.59) TSHRSLC22A1SLC22A2SMN1; SMN2DNM1
SCHEMBL11758406 0.82 TSHR (0.50) TSHRSLC22A1SLC22A2ALDH1A1DNM1
Tetrabuthylammonium SCHEMBL15822811 0.81 SLC22A1 (0.71) TSHRSLC22A1SLC22A2ALDH1A1TP53
SCHEMBL27494430 0.81 TSHR (0.81) TSHRSLC22A1SLC22A2ALDH1A1CYP3A4
Water SCHEMBL27972168 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1742976-B1 LOW-VISCOSITY ALLOPHANATES HAVING ACTINICALLY HARDENABLE GROUPS BAYER MATERIALSCIENCE AG (DE) 2010-09-15 EP claimed
EP-1727846-A1 PRODUCTION OF NOVEL RADIATION-HARDENING BINDING AGENTS Bayer MaterialScience AG (DE) 2006-12-06 EP claimed
WO-2005092943-A1 PRODUCTION OF NOVEL RADIATION-HARDENING BINDING AGENTS BAYER MATERIALSCIENCE AG (DE) 2005-10-06 WO claimed