Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.60 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.60 |
| ▸ | FLT1 | P17948 | 6/20 | 0.60 |
| ▸ | SRC | P12931 | 5/20 | 0.50 |
| ▸ | FLT4 | P35916 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.50 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.48 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.48 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.48 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.47 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.47 |
| ▸ | GAK | O14976 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22441436 | 1.00 | KDR (0.60) | KDRFGFR1FLT1SRCFLT4 | |
| SCHEMBL5201839 | 1.00 | KDR (0.60) | KDRFGFR1FLT1SRCFLT4 | |
| Hydrochloric Acid SCHEMBL6430860 | 0.99 | KDR (0.58) | KDRFGFR1FLT1SRCFLT4 | |
| SCHEMBL30465547 | 0.96 | FLT1 (0.54) | KDRFGFR1FLT1SRCFLT4 | |
| SCHEMBL2748495 | 0.96 | FLT1 (0.54) | KDRFGFR1FLT1SRCFLT4 | |
| SCHEMBL2746476 | 0.89 | EHMT2 (0.50) | KDRFGFR1FLT1SRCEGFR | |
| SCHEMBL29576504 | 0.88 | SRC (0.60) | SRCEGFRFGFR2GAK | |
| SCHEMBL29387468 | 0.88 | SRC (0.60) | SRCEGFRFGFR2GAK | |
| SCHEMBL359988 | 0.88 | SRC (0.60) | SRCEGFRFGFR2GAK | |
| SCHEMBL10188763 | 0.87 | ENPP1 (0.56) | KDRFGFR1FLT1SRCEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924092-B | Quinoline and quinazoline compounds and methods of use thereof | 斯汀格瑞治疗股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| EP-3941459-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF | Stingray Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |