Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.69 |
| ▸ | BTK | Q06187 | 7/20 | 0.69 |
| ▸ | EGFR | P00533 | 9/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | HCK | P08631 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.53 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.53 |
| ▸ | PRKDC | P78527 | 1/20 | 0.53 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.53 |
| ▸ | ITK | Q08881 | 3/20 | 0.49 |
| ▸ | ATR | Q13535 | 1/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16655308 | 1.00 | PIK3CD (0.69) | PIK3CDBTKEGFRABL1HCK | |
| SCHEMBL16655929 | 0.89 | EGFR (0.63) | PIK3CDBTKEGFRABL1HCK | |
| SCHEMBL16656044 | 0.88 | PIK3CD (0.61) | PIK3CDBTKEGFRABL1HCK | |
| SCHEMBL16655500 | 0.87 | BTK (0.57) | PIK3CDBTKEGFRITKATR | |
| SCHEMBL16665686 | 0.87 | BTK (0.57) | PIK3CDBTKEGFRITKATR | |
| SCHEMBL16655630 | 0.86 | PIK3CD (0.63) | PIK3CDBTKEGFRABL1HCK | |
| SCHEMBL23908595 | 0.85 | PIK3CD (0.68) | PIK3CDBTKEGFRABL1HCK | |
| SCHEMBL16655401 | 0.85 | PIK3CD (0.61) | PIK3CDBTKEGFRABL1HCK | |
| SCHEMBL16655311 | 0.85 | BTK (0.68) | PIK3CDBTKEGFRABL1HCK | |
| SCHEMBL16665842 | 0.85 | PIK3CD (0.61) | PIK3CDBTKEGFRABL1HCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941905-A1 | SUMO INHIBITOR COMPOUNDS AND USES THEREOF | Suvalent Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | claimed |