Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 18/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.57 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.57 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.57 |
| ▸ | CDK2 | P24941 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.57 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.57 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.57 |
| ▸ | HIPK3 | Q9H422 | 1/20 | 0.57 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353278 | 1.00 | CSNK2A2 (0.57) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 | |
| SCHEMBL30279919 | 1.00 | CSNK2A2 (0.57) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 | |
| SCHEMBL19742577 | 1.00 | CSNK2A2 (0.57) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 | |
| SCHEMBL19742507 | 1.00 | CSNK2A2 (0.57) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 | |
| SCHEMBL19742733 | 1.00 | CSNK2A2 (0.57) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 | |
| SCHEMBL19742440 | 0.92 | CSNK2A2 (0.59) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 | |
| SCHEMBL19742477 | 0.90 | CSNK2A2 (0.65) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 | |
| SCHEMBL19742433 | 0.90 | KCNH2 (0.65) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 | |
| SCHEMBL19742422 | 0.89 | CSNK2A2 (0.57) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 | |
| SCHEMBL19742656 | 0.89 | CSNK2A2 (0.60) | CSNK2A2CSNK2A1CSNK2BHIPK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3474855-B1 | CK2 INHIBITORS, COMPOSITIONS AND METHODS THEREOF | POLARIS PHARMACEUTICALS INC (US) | 2022-01-26 | — | — | EP | claimed |
| EP-3474855-B1 | CK2 INHIBITORS, COMPOSITIONS AND METHODS THEREOF | POLARIS PHARMACEUTICALS INC (US) | 2022-01-26 | — | — | EP | disclosed |