SCHEMBL29358136

SCHEMBL29358136

CCOC(=O)CNC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TLR2 O60603 4/20 0.46
▸ PTPN1 P18031 2/20 0.44
▸ MDM2 Q00987 1/20 0.43
▸ BCHE P06276 2/20 0.43
▸ ACHE P22303 2/20 0.43
▸ CACNA1F O60840 1/20 0.43
▸ CACNA1D Q01668 1/20 0.43
▸ CACNA1S Q13698 1/20 0.43
▸ CACNA1C Q13936 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29358858 0.93 TLR2 (0.46) TLR2PTPN1MDM2
SCHEMBL29355954 0.92 PTPN1 (0.48) TLR2PTPN1MDM2
SCHEMBL24235686 0.90 PTPN1 (0.54) PTPN1MDM2BCHEACHECACNA1F
SCHEMBL18576004 0.89 MDM2 (0.46) TLR2MDM2
SCHEMBL29692843 0.88 PTPN1 (0.43) TLR2PTPN1MDM2
SCHEMBL16093056 0.88 MDM2 (0.48) TLR2PTPN1MDM2
SCHEMBL10078351 0.88 MDM2 (0.48) TLR2PTPN1MDM2
SCHEMBL17322760 0.87 TLR2 (0.47) TLR2PTPN1MDM2
SCHEMBL12356377 0.86 TLR2 (0.54) TLR2
SCHEMBL24235738 0.86 PTPN1 (0.56) PTPN1MDM2BCHEACHECACNA1F

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600759-B2 Process of preparation of glucagon-like peptide-1 (GLP-1) receptor agonists and their analogs ENZENE BIOSCIENCES LIMITED (IN) 2026-04-14 — — US disclosed
US-20220153804-A1 PROCESS OF PREPARATION OF GLUCAGON-LIKE PEPTIDE-1 (GLP-1) RECEPTOR AGONISTS AND THEIR ANALOGS ENZENE BIOSCIENCES LIMITED (IN) 2022-05-19 — — US disclosed
EP-3941936-A2 PROCESS OF PREPARATION OF GLUCAGON-LIKE PEPTIDE-1 (GLP-1) RECEPTOR AGONISTS AND THEIR ANALOGS Enzene Biosciences Ltd. (IN) 2022-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153804-A1 PROCESS OF PREPARATION OF GLUCAGON-LIKE PEPTIDE-1 (GLP-1) RECEPTOR AGONISTS AND THEIR ANALOGS GLP1R, GIPR, GCGR TLR2 1925/4885PTPN1 330/4885MDM2 3435/4885
US-12600759-B2 Process of preparation of glucagon-like peptide-1 (GLP-1) receptor agonists and their analogs GLP1R, GIPR, GCG TLR2 1915/4885PTPN1 2094/4885MDM2 2390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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