⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068031 | 0.96 | — | — | |
| SCHEMBL11501693 | 0.75 | — | — | |
| SCHEMBL3945142 | 0.70 | — | — | |
| SCHEMBL235759 | 0.70 | KDM4E (0.36) | — | |
| SCHEMBL317785 | 0.70 | KDM4E (0.36) | — | |
| SCHEMBL698664 | 0.69 | — | — | |
| SCHEMBL14175014 | 0.69 | — | — | |
| SCHEMBL283751 | 0.69 | — | — | |
| SCHEMBL7569023 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL20605479 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 598 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11612606-B2 | 8-aminoisoquinoline compounds and uses thereof | GENENTECH, INC. (US) | 2023-03-28 | — | — | US | claimed |
| CN-113637005-A | KRAS inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2021-11-12 | — | — | CN | claimed |
| CN-110248937-A | 4, 5-Cyclic 1,2, 4-triazolones | 拜耳股份有限公司 | 2019-09-17 | — | — | CN | claimed |
| EP-3458445-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2019-03-27 | — | — | EP | claimed |
| EP-3324958-A1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | Newlink Genetics Corporation (US) | 2018-05-30 | — | — | EP | claimed |
| CN-107787340-A | The production of low emission polyurethane | 赢创德固赛有限公司 | 2018-03-09 | — | — | CN | claimed |
| CN-104558467-B | A kind of catalysts for polyurethanes and its application | 江苏奥斯佳材料科技有限公司 | 2018-02-23 | — | — | CN | claimed |
| WO-2017201161-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2017-11-23 | — | — | WO | claimed |
| US-9603829-B2 | HSP90 inhibitors with modified toxicity | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2017-03-28 | — | — | US | claimed |
| WO-2017019175-A1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | NEWLINK GENETICS CORPORATION (US) | 2017-02-02 | — | — | WO | claimed |
| EP-0328000-B1 | Indolocarbazole derivatives, process for their preparation and medicines containing same | GOEDECKE AG (DE) | 1995-01-18 | — | — | EP | claimed |
| US-5380746-A | Bis-(1H-indol-3-YL)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1995-01-10 | — | — | US | claimed |
| WO-1994010142-A1 | NEW SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS | MERCK & CO., INC. (US) | 1994-05-11 | — | — | WO | claimed |
| EP-0370236-B1 | INDOLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1991-12-27 | — | — | EP | claimed |
| EP-0370236-A1 | Indolocarbazole derivatives, processes for their preparation and their use as medicaments | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | claimed |
| US-4912107-A | Pyrrolocarbazole derivatives, compositions containing them, and methods for using them | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | claimed |
| CN-1035667-A | Indolocarbazole derivative and preparation method thereof and pharmaceutical composition | GOEDECKE AG (DE) | 1989-09-20 | — | — | CN | claimed |
| EP-0328000-A2 | Indolocarbazole derivatives, process for their preparation and medicines containing same | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1989-08-16 | — | — | EP | claimed |
| US-4849009-A | 2-arylmethyliminopyrazines pyrazines, compositions and method of combating undesirable plant growth and of regulating plant growth | CIBA-GEIGY CORPORATION (US) | 1989-07-18 | — | — | US | claimed |
| US-4332941-A | Cyclohexanones and cyclohexenones | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-06-01 | — | — | US | claimed |