SCHEMBL29359146

SCHEMBL29359146

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)O)C(C)C

nearest known ligand 0.83

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 20/20 0.83
▸ ECE1 P42892 1/20 0.77
▸ MUS81 Q96NY9 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27827907 1.00 GLP1R (0.83) GLP1RECE1MUS81
SCHEMBL29942457 1.00 GLP1R (0.83) GLP1RECE1MUS81
SCHEMBL29823404 1.00 GLP1R (0.83) GLP1RECE1MUS81
SCHEMBL31731011 1.00 GLP1R (0.83) GLP1RECE1MUS81
SCHEMBL29363146 1.00 GLP1R (0.83) GLP1RECE1MUS81
SCHEMBL30721588 1.00 GLP1R (0.83) GLP1RECE1MUS81
SCHEMBL29362765 1.00 GLP1R (0.83) GLP1RECE1MUS81
SCHEMBL30518507 1.00 GLP1R (0.83) GLP1RECE1MUS81
SCHEMBL30721547 0.99 GLP1R (0.83) GLP1R
SCHEMBL31072729 0.99 GLP1R (0.81) GLP1RECE1MUS81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 831 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260130971-A1 ACYLATED GLP-1 DERIVATIVE SCIWIND BIOSCIENCES CO LTD (CN) 2026-05-14 — — US claimed
US-12616739-B2 GLP-1 prodrugs and uses thereof NOVO NORDISK A/S (DK) 2026-05-05 — — US claimed
EP-3452049-B1 GLP-1 RECEPTOR LIGAND MOIETY CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF IONIS PHARMACEUTICALS INC (US) 2026-04-01 — — EP claimed
US-12508300-B2 Acylated GLP-1 derivative SCIWIND BIOSCIENCES CO., LTD (CN) 2025-12-30 — — US claimed
US-12435149-B2 Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (GIPR) in combination with GLP-1 agonists AMGEN INC. (US) 2025-10-07 — — US claimed
EP-3787631-B1 MODULATORS OF ORPHAN NUCLEAR RECEPTORS FOR NASH AND OTHER METABOLIC DISORDERS UNIV EMORY (US) 2025-09-10 — — EP claimed
US-20250276043-A1 Pharmaceutical Composition Containing GLP-1 Compound GAN & LEE PHARMACEUTICALS CO., LTD. (CN) 2025-09-04 — — US claimed
US-20250276068-A1 PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USES THEREOF BEIJING QL BIOPHARMACEUTICAL CO., LTD. (CN) 2025-09-04 — — US claimed
WO-2025133045-A1 FERMENTATION PROCESS NOVO NORDISK A/S (DK) 2025-06-26 — — WO claimed
WO-2025128968-A1 AZA GLP-1-BASED THERAPEUTIC ANALOGUES THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-06-19 — — WO claimed
CN-114621339-A Long-acting GLP-1 derivative 北京惠之衡生物科技有限公司 2022-06-14 — — CN claimed
CN-114621340-A Acylated long-acting GLP-1 derivative 北京惠之衡生物科技有限公司 2022-06-14 — — CN claimed
CN-113621046-B Use and method of polymer anion exchange filler in preparation of liraglutide 重庆宸安生物制药有限公司 2022-05-27 — — CN claimed
EP-3236937-B1 CONTROLLED-RELEASE FORMULATIONS CAMURUS AB (SE) 2022-05-04 — — EP claimed
EP-2637698-B1 DOUBLE-ACYLATED GLP-1 DERIVATIVES NOVO NORDISK AS (DK) 2022-04-20 — — EP claimed
CN-112522294-B Semi-recombinant preparation method of GLP-1 analogue 珠海冀百康生物科技有限公司 2022-03-22 — — CN claimed
CN-107412742-B Pharmaceutical composition comprising a GLP-1 peptide or exendin-4 peptide and a basal insulin peptide 诺沃—诺迪斯克有限公司 2022-03-15 — — CN claimed
US-20220062184-A1 Pharmaceutical Composition for Oral GLP-1 Administration Comprising a Tablet Core and Immediate Release Coating NOVO NORDISK AS (DK) 2022-03-03 — — US claimed
CN-107108714-B GLP-1 derivatives and uses thereof 诺和诺德股份有限公司 2022-02-08 — — CN claimed
CN-106999602-B GLP-1 derivatives and uses thereof 诺和诺德股份有限公司 2022-02-01 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12508300-B2 Acylated GLP-1 derivative GLP1R, GIPR, VIP GLP1R 1/4885ECE1 3559/4885MUS81 4877/4885
US-20260130971-A1 ACYLATED GLP-1 DERIVATIVE GLP1R, NPY1R, NPY4R GLP1R 1/4885ECE1 3502/4885MUS81 4770/4885
US-20250276068-A1 PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USES THEREOF GLP1R, GIPR, IAPP GLP1R 1/4885ECE1 1562/4885MUS81 4605/4885
US-12616739-B2 GLP-1 prodrugs and uses thereof GLP1R, SLC5A1, IAPP GLP1R 1/4885ECE1 542/4885MUS81 3970/4885
US-20220062184-A1 Pharmaceutical Composition for Oral GLP-1 Administration Comprising a Tablet Core and Immediate Release Coating GLP1R, GIPR, IAPP GLP1R 1/4885ECE1 1324/4885MUS81 4833/4885
US-20250276043-A1 Pharmaceutical Composition Containing GLP-1 Compound GLP1R, GIPR, SLC5A1 GLP1R 1/4885ECE1 2544/4885MUS81 4866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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