Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | PREP | P48147 | 3/20 | 0.56 |
| ▸ | FAP | Q12884 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.51 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.51 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28661857 | 0.91 | NPC1 (0.61) | DPP4NPC1GAARAB9APREP | |
| SCHEMBL22468385 | 0.91 | NPC1 (0.61) | DPP4NPC1GAARAB9APREP | |
| SCHEMBL31324125 | 0.87 | NPC1 (0.57) | DPP4NPC1GAARAB9APREP | |
| SCHEMBL31324097 | 0.86 | DPP4 (0.55) | DPP4NPC1GAARAB9APREP | |
| SCHEMBL30182765 | 0.86 | DPP4 (0.62) | DPP4NPC1GAARAB9APREP | |
| SCHEMBL31324091 | 0.85 | DPP4 (0.64) | DPP4NPC1GAARAB9APREP | |
| SCHEMBL30182960 | 0.84 | NPC1 (0.61) | DPP4NPC1GAARAB9APREP | |
| SCHEMBL31324117 | 0.84 | DPP4 (0.60) | DPP4NPC1GAARAB9APREP | |
| SCHEMBL30182769 | 0.84 | DPP4 (0.60) | DPP4PREPMMP1ALDH1A1 | |
| SCHEMBL29523956 | 0.83 | NPC1 (0.54) | DPP4NPC1GAARAB9APREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437913-A | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-3941462-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Achillion Pharmaceuticals, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |