Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLLT1 | Q03111 | 18/20 | 0.55 |
| ▸ | MLLT3 | P42568 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | YEATS2 | Q9ULM3 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395204 | 1.00 | MLLT1 (0.55) | MLLT1MLLT3MAOBYEATS2NAMPT | |
| SCHEMBL21394492 | 0.91 | MLLT1 (0.54) | MLLT1MLLT3MAOBYEATS2NAMPT | |
| SCHEMBL29357009 | 0.91 | MLLT1 (0.54) | MLLT1MLLT3MAOBYEATS2NAMPT | |
| SCHEMBL21394833 | 0.89 | MLLT1 (0.53) | MLLT1MLLT3MAOBYEATS2NAMPT | |
| SCHEMBL29355448 | 0.89 | MLLT1 (0.53) | MLLT1MLLT3MAOBYEATS2NAMPT | |
| SCHEMBL21394870 | 0.87 | MAOB (0.52) | MLLT1MLLT3MAOBYEATS2NAMPT | |
| SCHEMBL29356686 | 0.87 | MAOB (0.52) | MLLT1MLLT3MAOBYEATS2NAMPT | |
| SCHEMBL21394869 | 0.83 | MLLT1 (0.62) | MLLT1MLLT3MAOBYEATS2NAMPT | |
| SCHEMBL29357058 | 0.83 | MLLT1 (0.62) | MLLT1MLLT3MAOBYEATS2NAMPT | |
| SCHEMBL21394784 | 0.78 | GCK (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-3941908-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |