Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 5/20 | 0.51 |
| ▸ | PARP1 | P09874 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.48 |
| ▸ | PIM1 | P11309 | 3/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16226946 | 1.00 | MAPT (0.60) | MAPTMEN1KMT2AKDM4EUSP2 | |
| SCHEMBL29359531 | 1.00 | MAPT (0.60) | MAPTMEN1KMT2AKDM4EUSP2 | |
| Catenarin SCHEMBL29359362 | 0.85 | MEN1 (0.72) | MAPTMEN1KMT2AKDM4EUSP2 | |
| Catenarin SCHEMBL9175437 | 0.85 | MEN1 (0.72) | MAPTMEN1KMT2AKDM4EUSP2 | |
| Parietin SCHEMBL29356669 | 0.82 | MAPT (0.66) | MAPTMEN1KMT2AKDM4EUSP2 | |
| Parietin SCHEMBL16226462 | 0.82 | MAPT (0.66) | MAPTMEN1KMT2AKDM4EUSP2 | |
| SCHEMBL23198983 | 0.82 | EGFR (0.71) | MAPTMEN1KMT2AKDM4EUSP2 | |
| SCHEMBL23199004 | 0.82 | EGFR (0.71) | MAPTMEN1KMT2AKDM4EUSP2 | |
| Questin SCHEMBL29359576 | 0.79 | ELANE (0.73) | MAPTMEN1KMT2AKDM4EUSP2 | |
| Questin SCHEMBL15676283 | 0.79 | ELANE (0.73) | MAPTMEN1KMT2AKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943085-A2 | TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION | ETH Zurich (CH) | 2022-01-26 | — | — | EP | claimed |
| EP-3943085-A2 | TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION | ETH Zurich (CH) | 2022-01-26 | — | — | EP | disclosed |