⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13461879 | 0.63 | — | — | |
| SCHEMBL11067770 | 0.62 | — | — | |
| SCHEMBL28769670 | 0.62 | — | — | |
| SCHEMBL2527567 | 0.59 | — | — | |
| SCHEMBL18674866 | 0.57 | — | — | |
| SCHEMBL10032698 | 0.57 | — | — | |
| SCHEMBL5797902 | 0.57 | — | — | |
| SCHEMBL149795 | 0.57 | — | — | |
| SCHEMBL28130935 | 0.57 | — | — | |
| SCHEMBL6284138 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841276-B2 | Fulvene and fulvalene analogs and their use in treating cancers | EMORY UNIVERSITY (US) | 2014-09-23 | — | — | US | disclosed |
| US-20130338208-A1 | FULVENE AND FULVALENE ANALOGS AND THEIR USE IN TREATING CANCERS | U.S. GOVERNMANET AS REPRESENTED BY UNITED STATES DEPARTMENT OF VETERANS AFFAIRS (US) | 2013-12-19 | — | — | US | disclosed |
| CN-101772344-A | Fulvene and fulvalene analogs and their use in the treatment of cancer | UNIV EMORY (US) | 2010-07-07 | — | — | CN | disclosed |
| EP-2148666-A1 | FULVENE AND FULVALENE ANALOGS AND THEIR USE IN TREATING CANCERS | Emory University (US) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008137740-A1 | FULVENE AND FULVALENE ANALOGS AND THEIR USE IN TREATING CANCERS | EMORY UNIVERSITY (US) | 2008-11-13 | — | — | WO | disclosed |
| US-20080275016-A1 | For drug resistant cancers; antiinflammatory agents;degenerative or vascular diseases; blocking nitrogen oxide so growth of tumors is suppressed | U.S. GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS, THE | 2008-11-06 | — | — | US | disclosed |