⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL28860414 | 0.90 | — | — | |
| SCHEMBL13858924 | 0.86 | — | — | |
| SCHEMBL12962922 | 0.84 | — | — | |
| SCHEMBL17994210 | 0.81 | — | — | |
| SCHEMBL19444878 | 0.65 | — | — | |
| SCHEMBL8669889 | 0.62 | — | — | |
| SCHEMBL27459654 | 0.62 | — | — | |
| SCHEMBL4449428 | 0.61 | — | — | |
| SCHEMBL7145560 | 0.61 | — | — | |
| SCHEMBL28131660 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299214-B | A kind of Selective Separation or the method for recycling amino-compound | 华中科技大学 | 2019-11-12 | — | — | CN | disclosed |
| US-20190330142-A1 | INHIBITORS OF MTOR-DEPTOR INTERACTIONS AND METHODS OF USE THEREOF | THE UNITED STATES GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2019-10-31 | — | — | US | disclosed |
| EP-3535239-A1 | INHIBITORS OF MTOR-DEPTOR INTERACTIONS AND METHODS OF USE THEREOF | The Regents of The University of California (US) | 2019-09-11 | — | — | EP | disclosed |
| CN-109952287-A | Inhibitors of the MTOR-DEPTOR interaction and methods of use thereof | 加州大学评议会 | 2019-06-28 | — | — | CN | disclosed |
| CN-108299214-A | A kind of Selective Separation or the method for recycling amino-compound | 华中科技大学 | 2018-07-20 | — | — | CN | disclosed |
| CN-106458922-A | Affinity medicant conjugates | AF化学药品有限责任公司 | 2017-02-22 | — | — | CN | disclosed |
| US-8841276-B2 | Fulvene and fulvalene analogs and their use in treating cancers | EMORY UNIVERSITY (US) | 2014-09-23 | — | — | US | disclosed |
| US-20130338208-A1 | FULVENE AND FULVALENE ANALOGS AND THEIR USE IN TREATING CANCERS | U.S. GOVERNMANET AS REPRESENTED BY UNITED STATES DEPARTMENT OF VETERANS AFFAIRS (US) | 2013-12-19 | — | — | US | disclosed |
| CN-101772344-A | Fulvene and fulvalene analogs and their use in the treatment of cancer | UNIV EMORY (US) | 2010-07-07 | — | — | CN | disclosed |
| EP-2148666-A1 | FULVENE AND FULVALENE ANALOGS AND THEIR USE IN TREATING CANCERS | Emory University (US) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008137740-A1 | FULVENE AND FULVALENE ANALOGS AND THEIR USE IN TREATING CANCERS | EMORY UNIVERSITY (US) | 2008-11-13 | — | — | WO | disclosed |
| US-20080275016-A1 | For drug resistant cancers; antiinflammatory agents;degenerative or vascular diseases; blocking nitrogen oxide so growth of tumors is suppressed | U.S. GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS, THE | 2008-11-06 | — | — | US | disclosed |