Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 12/20 | 0.68 |
| ▸ | DRD2 | P14416 | 8/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | DRD5 | P21918 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.51 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.51 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.51 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.51 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.51 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.51 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.51 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.51 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22445614 | 1.00 | DRD1 (0.68) | DRD1DRD2CYP3A4MEN1CYP2D6 | |
| SCHEMBL22461447 | 0.81 | CYP3A4 (0.66) | DRD1DRD2CYP3A4MEN1CYP2D6 | |
| SCHEMBL6010798 | 0.81 | CYP3A4 (0.66) | DRD1DRD2CYP3A4MEN1CYP2D6 | |
| Bromide SCHEMBL8905619 | 0.81 | PARP1 (0.60) | DRD1DRD2CYP3A4MEN1CYP2D6 | |
| SCHEMBL11799212 | 0.81 | SLC6A2 (0.60) | DRD1DRD2 | |
| SCHEMBL15096889 | 0.80 | CYP3A4 (1.00) | DRD1DRD2CYP3A4MEN1CYP2D6 | |
| SCHEMBL1076323 | 0.80 | CYP3A4 (1.00) | DRD1DRD2CYP3A4MEN1CYP2D6 | |
| Hydrochloric Acid SCHEMBL11803408 | 0.80 | SLC6A2 (0.59) | DRD1DRD2 | |
| SCHEMBL11639387 | 0.78 | MEN1 (0.60) | DRD1DRD2CYP3A4MEN1CYP2D6 | |
| SCHEMBL29356733 | 0.78 | MEN1 (0.60) | DRD1DRD2CYP3A4MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3941905-A1 | SUMO INHIBITOR COMPOUNDS AND USES THEREOF | Suvalent Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |