Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 1.00 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186260 | 1.00 | GRM1 (1.00) | GRM1KDM1AMAOAMAOBAIMP2 | |
| SCHEMBL7385755 | 0.88 | GRM1 (0.78) | GRM1KDM1AMAOAMAOBAIMP2 | |
| SCHEMBL6770376 | 0.85 | GRM1 (0.73) | GRM1MAOAMAOB | |
| SCHEMBL6770374 | 0.85 | GRM1 (0.73) | GRM1MAOAMAOB | |
| SCHEMBL6770054 | 0.80 | GRM1 (0.67) | GRM1 | |
| SCHEMBL6898191 | 0.80 | GRM1 (0.67) | GRM1 | |
| SCHEMBL6770051 | 0.80 | GRM1 (0.67) | GRM1 | |
| SCHEMBL6898189 | 0.80 | GRM1 (0.67) | GRM1 | |
| SCHEMBL7422783 | 0.80 | GRM1 (0.67) | GRM1 | |
| SCHEMBL7679875 | 0.79 | GRM1 (0.65) | GRM1KDM1AMAOAMAOBAIMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250367293-A1 | COMBINATION THERAPY USING RILUZOLE TO ENHANCE TUMOR SENSITIVITY TO IONIZING RADIATION | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2025-12-04 | — | — | US | disclosed |
| CN-120078772-A | Application of A61603 as anti-liver cancer therapeutic drug | 上海交通大学医学院附属仁济医院 | 2025-06-03 | — | — | CN | disclosed |
| US-12318449-B2 | Combination therapy using riluzole to enhance tumor sensitivity to ionizing radiation | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2025-06-03 | — | — | US | disclosed |
| US-20240100018-A1 | COMPOUNDS FOR THE TREATMENT OF A DISEASE OR DISORDER, METHODS FOR IDENTIFYING SAID COMPOUNDS | CEDARS-SINAI MEDICAL CENTER | 2024-03-28 | — | — | US | disclosed |
| US-20240042033-A1 | COMBINATION THERAPY USING RILUZOLE TO ENHANCE TUMOR SENSITIVITY TO IONIZING RADIATION | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2024-02-08 | — | — | US | disclosed |
| US-11813331-B2 | Combination therapy using riluzole to enhance tumor sensitivity to ionizing radiation | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-11-14 | — | — | US | disclosed |
| US-20220096636-A1 | COMBINATION THERAPY USING RILUZOLE TO ENHANCE TUMOR SENSITIVITY TO IONIZING RADIATION | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2022-03-31 | — | — | US | disclosed |
| US-11229704-B2 | Combination therapy using riluzole to enhance tumor sensitivity to ionizing radiation | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2022-01-25 | — | — | US | disclosed |