Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29360961 | 0.89 | GAA (0.46) | GAAHDAC4HDAC6MAPK1HDAC3 | |
| SCHEMBL29361246 | 0.85 | PTPN2 (0.43) | GAAHDAC4HDAC6MAPK1HDAC3 | |
| SCHEMBL29359939 | 0.83 | CYP4F2 (0.41) | GAAHDAC4HDAC6MAPK1HDAC3 | |
| SCHEMBL29358255 | 0.82 | GAA (0.39) | GAAHDAC4HDAC6MAPK1HDAC3 | |
| SCHEMBL5128149 | 0.74 | GAA (0.63) | GAAHDAC4HDAC6MAPK1HDAC3 | |
| SCHEMBL16863717 | 0.74 | GAA (0.50) | GAAHDAC4HDAC6MAPK1HDAC3 | |
| SCHEMBL168837 | 0.72 | GAA (0.71) | GAAMAPK1TSHRALDH1A1MAPT | |
| SCHEMBL29359967 | 0.72 | GAA (0.49) | GAAMAPK1TSHRCA12CA1 | |
| SCHEMBL20269597 | 0.72 | GAA (0.49) | GAAMAPK1TSHRCA12CA1 | |
| SCHEMBL8630776 | 0.72 | GAA (0.49) | GAAMAPK1TSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022017975-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-01-27 | — | — | WO | disclosed |