Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | MARK3 | P27448 | 1/20 | 0.39 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 10/20 | 0.39 |
| ▸ | CDK1 | P06493 | 3/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.37 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | LYN | P07948 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30847419 | 0.80 | CCNB2 (0.46) | ELANECDK1CCNB1CCNB2CCNB3 | |
| SCHEMBL27153842 | 0.80 | CCNB2 (0.46) | ELANECDK1CCNB1CCNB2CCNB3 | |
| SCHEMBL31710700 | 0.80 | ELANE (0.51) | ELANECDK1CCNB1CCNB2CCNB3 | |
| SCHEMBL23163135 | 0.77 | CDK1 (0.43) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL24710386 | 0.77 | CCND1 (0.38) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL18253164 | 0.76 | JAK1 (0.45) | PIM1MARK3MAP4K2CAMK2BPIM3 | |
| SCHEMBL31219308 | 0.76 | ELANE (0.47) | ELANEPOLBDTYMK | |
| SCHEMBL13425915 | 0.76 | ELANE (0.47) | ELANEPOLBDTYMK | |
| SCHEMBL16562895 | 0.75 | ELANE (0.44) | ELANEPOLBDTYMK | |
| SCHEMBL295518 | 0.74 | ELANE (0.55) | ELANEPOLBDTYMK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022020342-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. (US) | 2022-01-27 | — | — | WO | disclosed |