Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1277734 | 0.91 | MAPK1 (0.31) | MAPK1JAK2JAK1TYK2JAK3 | |
| SCHEMBL1277737 | 0.91 | MAPK1 (0.31) | MAPK1JAK2JAK1TYK2JAK3 | |
| SCHEMBL1278419 | 0.91 | MAPK1 (0.31) | MAPK1JAK2JAK1TYK2JAK3 | |
| SCHEMBL1278417 | 0.91 | MAPK1 (0.31) | MAPK1JAK2JAK1TYK2JAK3 | |
| SCHEMBL1277343 | 0.89 | MAPK1 (0.30) | MAPK1 | |
| SCHEMBL1277340 | 0.89 | MAPK1 (0.30) | MAPK1 | |
| SCHEMBL1278084 | 0.89 | HTR2B (0.32) | MAPK1JAK2JAK1TYK2JAK3 | |
| SCHEMBL1278081 | 0.89 | HTR2B (0.32) | MAPK1JAK2JAK1TYK2JAK3 | |
| SCHEMBL1277772 | 0.87 | MAPK1 (0.31) | MAPK1JAK2JAK1TYK2JAK3 | |
| SCHEMBL1277776 | 0.87 | MAPK1 (0.31) | MAPK1JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220081-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG Life Sciences Ltd. (KR) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009082152-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG LIFE SCIENCES LTD. (KR) | 2009-07-02 | — | — | WO | disclosed |